Increased levels of Serum Nitrogen oxides are indicators of Post-treatment response in Mood disorder patients with Acute episodes

Background: Nitrogen Oxides (NOx) has an important role in mood disorders. This study aims to investigate whether serum NOx levels are associated with bipolar disorder, manic episodes (BD-ME) and major depressive disorder, depressive episodes (MDD-DE), and to evaluate the impact of treatments on NOx levels and symptoms severity in BD-ME and MDD-DE patients.
Methods: We enrolled 20 patients with BD-ME, 18 with MDD-DE, and 80 healthy subjects. Serum NOx levels were measured with assay kits. Symptom severity was evaluated using the Young Mania Rating Scale (YMRS) for BD-ME and the Hamilton Depression Rating Scale (HAM-D) for MDDDE. We collected and analyzed patients’ NOx, YMRS, and HAM-D data while pre-treatment (admission) and post-treatment (discharge).

For more details Abstract: http://www.jneuropsychiatry.org/abstract/increased-levels-of-serum-nitrogen-oxides-are-indicators-of-posttreatment-response-in-mood-disorder-patients-with-acute--11796.html
PDF Link: http://www.jneuropsychiatry.org/peer-review/increased-levels-of-serum-nitrogen-oxides-are-indicators-of-posttreatment-response-in-mood-disorder-patients-with-acute-.pdf
Full Text Link: http://www.jneuropsychiatry.org/peer-review/increased-levels-of-serum-nitrogen-oxides-are-indicators-of-posttreatment-response-in-mood-disorder-patients-with-acute-episodes.html

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